Seidinova Aigerim
International Kazakh-Turkish University, Republic of Kazakhstan
Title: Comparative lipid evaluation in patients with type 2 diabetes mellitus on continuous subcutaneous insulin infusion and multiple daily injections.
Biography
Biography: Seidinova Aigerim
Abstract
Background: Type 2 diabetes accounts for 90% of all types of diabetes [1]. Diabetes mellitus is a chronic metabolic disease that often exacerbates lipid metabolism, affects weight. Several studies have been devoted to the study of body mass index (BMI) in people with diabetes on a continuous subcutaneous insulin infusion (CSII) [2, 3, 4]. Extremely little has been studied about the lipid changes in patients with diabetes on the CSII. Thus, people with type 2 diabetes need more detailed research on (CSII) [5].
The purpose: To study lipid parameters in patients with type 2 diabetes on a CSII and MDI.
Materials and methods: In this research work, lipid data (Cholesterol, Triglycerides, HDL, LDL) were compared in patients with type 2 diabetes who were on CSII (n = 105) and MDI (n = 105). All patients were divided into subgroups by age (45-50; 51-55; 56-65 years); on the duration of the disease (5-10 years; 11-15 years; 16 years and above) and on gender differences (men and women).
Results: Comparative analysis showed high statistical confidence between the average cholesterol levels of the studied groups at the level of p ≤ 0.001. Similarly, it was with HDL, at the level of p ≤ 0.001. When comparing only in women, LDL was found to be statistically significant (p ≤ 0.05). Comparison of the average values of triglycerides by sex, age, duration of the disease was not found a significant statistical significance (p> 0.05).
Conclusion: The method of treatment of CSII influenced the level of lipids, in patients cholesterol was lower compared to the MDI. However, CSII did not affect triglycerides, only in female.