Mohammad Jalali
Shahid Beheshti University of Medical Sciences, Iran
Title: The effects of vitamin D supplementation on anthropometric indices in children and adolescents: A systematic review and meta-analysis of randomized controlled trials
Biography
Biography: Mohammad Jalali
Abstract
High prevalence of obesity and vitamin D deficiency are two health concerns in childhood and adolescence. The effects of vitamin D supplementation on anthropometric indices were evaluated in several trials, but the results were inconclusive. The present meta-analysis aimed to evaluate the effects of vitamin D supplementation on anthropometric indices of children and adolescents. PubMed, Embase, Scopus and Web of Science were systemically searched to identify the relevant records investigating the effect of vitamin D supplementation on body composition in children and adolescents up to 2022. In the case of heterogeneity among studies, fixed and random effect models were used. Indeed, potential publication bias was detected using Egger’s regression tests. After excluding irrelevant papers, five records with eight separate studies were included in this meta-analysis. Pooled results of the included literature showed a significant increase in body weight (Standardized Mean Difference (SMD)=0.148, 95% Confidence Interval (CI): [0.009,0.286], p=0.037), fat free mass (SMD=0.384, 95% CI: (0.119,0.649), p=0.004) and serum 25(OH)D level (SMD=1.071, 95% CI: (0.591,1.551), p=0.000) after the intervention. However, no significant change was observed in height, Body Mass Index (BMI) and Parathyroid Hormone (PTH) following vitamin D supplementation. This meta-analysis of available clinical trials showed a significant increment in weight, fat free mass and 25(OH)D level following vitamin D supplementation in childhood and adolescents.