International Conference on Childhood Obesity & Child Development August 29-30, 2016 Atlanta, USA

Lisha He is doing her PhD at the age of 29 years from China Academy of Chinese Medical Sciences and doctoral studies from Beijing University of Chinese Medicine. She has published more than 15 papers both in China and international reputed journals.

Metabolic syndrome represents a group of complex metabolic diseases, which is characterized by obesity, combined with impaired glucose levels, hypertension and hyperlipidemia. Traditional Chinese Medicine has rich experience in solving this series of problems through an overall adjustment var multi ways and targets, but the exact molecular mechanisms are unclear. Long noncoding RNAs (lncRNAs) represent a subgroup of noncoding RNAs that are longer than 200 nucleotides. Notably, the deregulation of lncRNAs has also been shown to result in aberrant gene expression that contributes to the progression of metabolic syndrome treatment. Previous studies conducted by our research team have confirmed the effectiveness of TCM Prescription Jiangtang Tiaozhi on reducing body weight, blood sugar and blood lipids. In the study, patients with type 2 diabetes with obesity and hyperlipidemia were treated by traditional Chinese medicine Jiangtang Tiaozhi Prescription of 24 weeks, we chosed 6 effective cases and 6 invalid cases as control to analysis the molecular mechanism of TCM treatment. According to the research of LncRNA microarray, GO analysis, Pathway analysis, and qPCR validation, we found out the target LncRNAs LDHA, XLOC_011623, as well as their associated mRNAs LDHA, ATP6V0C were contribute to the good outcome of Jiangtang Tiaozhi Formula.

Mansi Naik, she has completed her schooling from St. Francis of Asissi Convent High School, Navsari, India and 1st, 2nd and 3rd year of Med School (M.B;B.S.) from Government medical college, Bhavnagar, India at the age of 21 years. she stood among the Top 500 students of the state among 2,00,000 students who appeared in the State Board and got admission in Medical School, India on the basis of Government Scholarship. She has secured First Class throughout her academics in Med School and also has zealously participated in many quizes and oral presentations at College level. She has participated in the IAPSM- World Health Day 2016 Quiz on “Beat Diabetes” organized by Community Medicine department of GMC, Bhavnagar. Presented a project on "Knowledge, attitude and practices of post-natal mothers for early initiation of breast-feeding" to the members of the department of Community Medicine and students of Government Medical College, Bhavnagar-2015. Participated in the Poster competition "From farm to plate" held on World Health Day-2015 by the Community Medicine department, GMC, Bhavnagar.Attended the Medical Quizes & debates during the National Medical Organisation Conference held at Rajendra Institute of Medical Sciences, Ranchi, Jharkhand - 2014.Worked as an active member of the Anti-Tobacco campaign held in GMC, Bhavnagar during 2012-13.

In today’s 21st century, because of the increasing prevalence of stressful and hectic lifestyle, women have started paying less attention to their health and often ignore some serious health issues which result in deleterious outcome. Among them, the group of women which suffer the most are the Post-natal women who along with themselves also risk the lives of their new-borns by such careless methods of nutrition. This eventually brings me to the prime objectives of my project which are to study the breast-feeding practices and its time of initiation among them, awareness of colostrum-feeding, pre-lacteal feeding and supplementary feeding practices among them. My project is basically a cross-sectional study among 50 post-natal women in the Obs and Gynec Department of Sir-T hospital, Bhavnagar. The study is based on one to one interaction directly with the mothers as well as their relatives with the help of pre-tested and structured questionarres after acquiring their verbal consent. My study begins with explaining the advantages, disadvantages, exact duration, contra-indications of breast-feeding as suggested by the American Pediatrics Association. Thereby, emphasizing the nutritional, anti-infective, anti-fertility, psycho-social and economic advantages of breast-feeding. The study includes the rural and urban patterns of breast-feeding practices in the developing and developed counties. Therefore, since the beneficial effects of breast-feeding is concerned with the need of proper Breast-feeding practices, the perks of my study were having a small counselling talk with each post-natal woman who was being a part of the study and sessions of “Breast-feeding Awareness” among small groups of them, regarding ‘Correct’ breast-feeding technique. Another noticable point of such counselling reflected signifance of breast-feeding on not only for infant’s overall health but also for mother’s own health. As promoted by the American Academy for Pediatrics and American Diabetic Association, my study project concludes that breast-feeding is the best source for infant nutrition and helps to prevent Infant malnutrition as well as Obesity.

Han Wang has completed her baccalaureate at the age of 24 years from Nanjing University of Chinese Medicine and master of studies from Chinese Academy of traditional Chinese Medicine. She has published 5 papers in reputed journals.

The rapidly increasing incidence of diabetes mellitus (DM) is becoming a major public health issue. As one of the important parts in complementary and alternative therapies, traditional Chinese medicine (TCM) is promising in treating Obese type 2 diabetes mellitus. In this review, we summarize the advantage of TCM in treating diabetes that aim to improve the clinical efficacy of TCM. Our approach is as follows: NEW THEORY :Pi-dan is a significant conception, which comes from Inner Canon of Huangdi. From the vivid description of Pi-dan in Inner Canon of Huangdi, we consider that the formation and process of Pi-dan is equivalent to metabolic syndrome. They all have the same etiological factor: obesity. The core of the Pathogenesis is fullness in the middle-jiao, and inner heat. The stagnation of middle-jiao makes the qi stagnation. They can result in diabetes, hypertension, hyperlipidemia, fatty liver, gout and a series of severity vascular complication. METHODS: Emphasizing heat-clearing in the early and middle stage of T2DM and invigorating blood circulation throughout the whole process of obese T2DM are two innovative methods to treat T2DM. FORMULAS and HERBS: Choosing formulas and herbs based on the combination of TCM theory and Modern pharmacology. DOSE: Reasonable drug dose plays an important role in the treatment of DM and a close relationship exists between dose and clinical efficacy. Fifty-four obese type 2 diabetic patients from low dosage group (20 cases), medium dosage group (19 cases) and high dosage group (15 cases) were treated with different dosage of Gegen Qin Lian Decoction for 12 weeks. Fasting blood-glucose (FBG), postprandial blood sugar (PBG) and Hemoglobin A1c (HbAlc) were determined before and after treatment. The result indicated that every dosage group could control the blood glucose in some extent. High dosage group showed best effect, and then followed by the medium dosage group and the low dosage group.

Eun Young Lee has completed her PhD at the age of 33 years from Yonsei University College of Medicine. She is a Clinical Assistant Professor, Seoul St. Mary’s Hospital, The Catholic University of Korea, Seoul, South Korea. Se has published more than 20 papers in reputed journals and has been researching in areas related diabetes, metabolism, obesity, and aging.

In this study, we investigated which factors related to eating behavior are associated with obesity among Korean children. We recruited a total of 393 children aged 10-14 years from a community-based sample. Body mass index (BMI, kg/m2) was used to define overweight (≥85 percentile) and obese (≥95 percentile or 25 kg/m2). Factors related to eating behavior were assessed using the food craving questionnaire –trait (FCQ-T), -state, Dutch eating behavior questionnaire (DEBQ), and three factor eating questionnaire (TFEQ). Obese children showed greater waist circumference, body fat percentage, and higher blood pressure compare to non-obese children. In terms of factors related to eating behavior, obese children showed higher score in preoccupation with food, lack of control, intense desire to eat, dietary and cognitive restraint, and disinhibition. These traits were more significant in boys than girls. Most factors related to eating behavior were significantly correlated with BMI, except positive and negative reinforcement, feelings of hunger, and emotional eating. In regression analysis, only three factors related to eating behavior were significantly associated with obesity (odds ratio [95% CI], 1.364 [1.027-1.810] for FCQ-T preoccupation with food, 1.136 [1.052-1.226] for DEBQ dietary restraint, and 1.435 [1.005-2.050] for TFEQ disinhibition). In conclusion, several factors related to eating behavior, such as preoccupation with food, dietary restraint, and disinhibition, were significantly associated with obesity in Korean children. Given that eating habits formed in childhood track to adulthood, further investigation to identify factors related to eating behavior and their relationship with obesity may be helpful to prevent and manage obesity. ※ This research was supported by Social Problem Solving Research Program through the National Research Foundation for Korea (NRF) funded by the Ministry of Science, ICT and Future Planning (2013M3C8A2A02078508).